*= Confirmed Main Characters

1. Ashrah (DLC)

2. Baraka

3. Candyman (Guest)

4. D’Vorah

5. Ermac (DLC)

6. Erron Black (DLC)

7. Fujin

8. Homelander (The Boys) (Guest)

9. Jade

10. Jax Briggs

11. Johnny Cage*

12. Kano

13. Kenshi*

14. Kitana*

15. Kotal Khan

16. Kung Lao*

17. Liu Kang*

18. Mileena*

19. Nitara (DLC)

20. Omni-Man (Invincible) (Guest)

21. Peacemaker (Guest)

22. Quan Chi (DLC)

23. Raiden*

24. Rain*

25. Reptile (DLC)

26. Scorpion*

27. Shang Tsung (DLC)

28. Shao Khan

29. Skarlet

30. Smoke*

31. Sonya Blade

32. Stryker

33. Sub-Zero*

34. Tanya

35. Vera Briggs

36. Vex'ahila (The Legend Of Vox Machina) (Guest)

*= Confirmed Kameo Characters

1. Billy Butcher (The Boys) (Guest)

2. Cyrax*

3. Darrius (DLC)

4. Frost*

5. Goro*

6. Invincible (Guest)

7. Jade

8. Jax Briggs*

9. Johnny Cage

10. Kano*

11. Khameleon (DLC)

12. Kintaro (DLC)

13. Kitana

14. Kung Lao*

15. Li Mei (DLC)

16. Mileena

17. Mokap (DLC)

18. Sareena (DLC)

19. Scorpion*

20. Sektor*

21. Sheeva (DLC)

22. Sindel

23. Skarlet (DLC)

24. Sonya Blade*

25. Stryker*

26. Sub-Zero*